Cancer data science concepts for undergraduates

Package: YESCDSbook
Authors: Vincent Carey [aut, cre]
Compiled: 2023-12-13
Package version: 0.98.4
R version: R Under development (unstable) (2023-11-22 r85609)
BioC version: 3.19
License: MIT + file LICENSE

Welcome

This is the landing page of the BiocBook entitled β€œCancer data science concepts for undergraduates”

This book introduces the reader to the concepts mapped below:

coggle

The YESCDS R package includes data structures and functions used in this book.

Docker image

A Docker image built from this repository is available here:

πŸ‘‰ ghcr.io/vjcitn/yescdsbook 🐳

Get started now πŸŽ‰

You can get access to all the packages used in this book in < 1 minute, using this command in a terminal:

bash
docker run -it ghcr.io/vjcitn/yescdsbook:devel R

RStudio Server

An RStudio Server instance can be initiated from the Docker image as follows:

bash
docker run \
    --volume <local_folder>:<destination_folder> \
    -e PASSWORD=OHCA \
    -p 8787:8787 \
    ghcr.io/vjcitn/yescdsbook:devel

The initiated RStudio Server instance will be available at https://localhost:8787.

Acknowledgments

Contributors:

  • Alexandru Mahmoud, Channing Division of Network Medicine, Mass General Brigham
  • Brittany Michel, Dana-Farber Cancer Institute
  • Latrice Landry, Perelman School of Medicine, University of Pennsylvania
  • Karen Burns White, Dana-Farber Cancer Institute
  • Vincent Carey, Channing Division of Network Medicine, Mass General Brigham

This project is supported in part by

  • NSF ACCESS Allocation BIR190004 β€œEngineering and disseminating a software and analysis ecosystem for genomic data science”

  • Chan-Zuckerberg Initiative EOSS Diversity & Inclusiveness EOSS-DI-0000000033 β€œBioconductor: Sustaining a Worldwide Community of Genome Data Scientists”

  • National Cancer Institute 5U24CA180996-08 β€œCancer Genomics: Integrative and Scalable Solutions in R/Bioconductor”

  • National Human Genome Research Institute 2U24HG004059-17 β€œBioconductor: An Open-Source, Open-Development Computing Resource for Genomics”

Session info

sessioninfo::session_info(
    installed.packages()[,"Package"], 
    include_base = TRUE
)
##  ─ Session info ────────────────────────────────────────────────────────────
##   setting  value
##   version  R Under development (unstable) (2023-11-22 r85609)
##   os       Ubuntu 22.04.3 LTS
##   system   x86_64, linux-gnu
##   ui       X11
##   language (EN)
##   collate  C
##   ctype    en_US.UTF-8
##   tz       Etc/UTC
##   date     2023-12-13
##   pandoc   3.1.1 @ /usr/local/bin/ (via rmarkdown)
##  
##  ─ Packages ────────────────────────────────────────────────────────────────
##   package              * version   date (UTC) lib source
##   abind                  1.4-5     2016-07-21 [2] CRAN (R 4.4.0)
##   AnnotationDbi          1.65.2    2023-11-03 [2] Bioconductor
##   AnnotationHub          3.11.1    2023-12-11 [2] Bioconductor 3.19 (R 4.4.0)
##   askpass                1.2.0     2023-09-03 [2] CRAN (R 4.4.0)
##   base                 * 4.4.0     2023-11-26 [3] local
##   base64enc              0.1-3     2015-07-28 [2] CRAN (R 4.4.0)
##   beeswarm               0.4.0     2021-06-01 [2] CRAN (R 4.4.0)
##   Biobase                2.63.0    2023-10-24 [2] Bioconductor
##   BiocBaseUtils          1.5.0     2023-10-24 [2] Bioconductor
##   BiocFileCache          2.11.1    2023-10-26 [2] Bioconductor
##   BiocGenerics           0.49.1    2023-11-01 [2] Bioconductor
##   BiocManager            1.30.22   2023-08-08 [2] CRAN (R 4.4.0)
##   BiocStyle              2.31.0    2023-10-24 [2] Bioconductor
##   BiocVersion            3.19.1    2023-10-26 [2] Bioconductor
##   Biostrings             2.71.1    2023-10-25 [2] Bioconductor
##   bit                    4.0.5     2022-11-15 [2] CRAN (R 4.4.0)
##   bit64                  4.0.5     2020-08-30 [2] CRAN (R 4.4.0)
##   bitops                 1.0-7     2021-04-24 [2] CRAN (R 4.4.0)
##   blob                   1.2.4     2023-03-17 [2] CRAN (R 4.4.0)
##   bookdown               0.37      2023-12-01 [2] CRAN (R 4.4.0)
##   boot                   1.3-28.1  2022-11-22 [3] CRAN (R 4.4.0)
##   brew                   1.0-8     2022-09-29 [2] CRAN (R 4.4.0)
##   brio                   1.1.3     2021-11-30 [2] CRAN (R 4.4.0)
##   bslib                  0.6.1     2023-11-28 [2] CRAN (R 4.4.0)
##   cachem                 1.0.8     2023-05-01 [2] CRAN (R 4.4.0)
##   callr                  3.7.3     2022-11-02 [2] CRAN (R 4.4.0)
##   class                  7.3-22    2023-05-03 [3] CRAN (R 4.4.0)
##   classInt               0.4-10    2023-09-05 [2] CRAN (R 4.4.0)
##   cli                    3.6.2     2023-12-11 [2] CRAN (R 4.4.0)
##   clipr                  0.8.0     2022-02-22 [2] CRAN (R 4.4.0)
##   cluster                2.1.6     2023-12-01 [3] CRAN (R 4.4.0)
##   codetools              0.2-19    2023-02-01 [3] CRAN (R 4.4.0)
##   colorspace             2.1-0     2023-01-23 [2] CRAN (R 4.4.0)
##   commonmark             1.9.0     2023-03-17 [2] CRAN (R 4.4.0)
##   compiler               4.4.0     2023-11-26 [3] local
##   cpp11                  0.4.7     2023-12-02 [2] CRAN (R 4.4.0)
##   crayon                 1.5.2     2022-09-29 [2] CRAN (R 4.4.0)
##   credentials            2.0.1     2023-09-06 [2] CRAN (R 4.4.0)
##   crosstalk              1.2.1     2023-11-23 [2] CRAN (R 4.4.0)
##   curatedTCGAData        1.25.0    2023-10-31 [2] Bioconductor
##   curl                   5.2.0     2023-12-08 [2] CRAN (R 4.4.0)
##   data.table             1.14.10   2023-12-08 [2] CRAN (R 4.4.0)
##   datasets             * 4.4.0     2023-11-26 [3] local
##   DBI                    1.1.3     2022-06-18 [2] CRAN (R 4.4.0)
##   dbplyr                 2.4.0     2023-10-26 [2] CRAN (R 4.4.0)
##   DelayedArray           0.29.0    2023-10-24 [2] Bioconductor
##   desc                   1.4.2     2022-09-08 [2] CRAN (R 4.4.0)
##   devtools               2.4.5     2022-10-11 [2] CRAN (R 4.4.0)
##   diffobj                0.3.5     2021-10-05 [2] CRAN (R 4.4.0)
##   digest                 0.6.33    2023-07-07 [2] CRAN (R 4.4.0)
##   docopt                 0.7.1     2020-06-24 [2] CRAN (R 4.4.0)
##   downlit                0.4.3     2023-06-29 [2] CRAN (R 4.4.0)
##   dplyr                  1.1.4     2023-11-17 [2] CRAN (R 4.4.0)
##   DT                     0.31      2023-12-09 [2] CRAN (R 4.4.0)
##   e1071                  1.7-14    2023-12-06 [2] CRAN (R 4.4.0)
##   ellipsis               0.3.2     2021-04-29 [2] CRAN (R 4.4.0)
##   evaluate               0.23      2023-11-01 [2] CRAN (R 4.4.0)
##   ExperimentHub          2.11.1    2023-12-11 [2] Bioconductor 3.19 (R 4.4.0)
##   fansi                  1.0.6     2023-12-08 [2] CRAN (R 4.4.0)
##   farver                 2.1.1     2022-07-06 [2] CRAN (R 4.4.0)
##   fastmap                1.1.1     2023-02-24 [2] CRAN (R 4.4.0)
##   filelock               1.0.3     2023-12-11 [2] CRAN (R 4.4.0)
##   fontawesome            0.5.2     2023-08-19 [2] CRAN (R 4.4.0)
##   forcats                1.0.0     2023-01-29 [2] CRAN (R 4.4.0)
##   foreign                0.8-86    2023-11-28 [3] CRAN (R 4.4.0)
##   fs                     1.6.3     2023-07-20 [2] CRAN (R 4.4.0)
##   generics               0.1.3     2022-07-05 [2] CRAN (R 4.4.0)
##   GenomeInfoDb           1.39.1    2023-11-08 [2] Bioconductor
##   GenomeInfoDbData       1.2.11    2023-12-13 [2] Bioconductor
##   GenomicRanges          1.55.1    2023-10-29 [2] Bioconductor
##   gert                   2.0.1     2023-12-04 [2] CRAN (R 4.4.0)
##   ggbeeswarm             0.7.2     2023-04-29 [2] CRAN (R 4.4.0)
##   ggplot2                3.4.4     2023-10-12 [2] CRAN (R 4.4.0)
##   gh                     1.4.0     2023-02-22 [2] CRAN (R 4.4.0)
##   gitcreds               0.1.2     2022-09-08 [2] CRAN (R 4.4.0)
##   glue                   1.6.2     2022-02-24 [2] CRAN (R 4.4.0)
##   graphics             * 4.4.0     2023-11-26 [3] local
##   grDevices            * 4.4.0     2023-11-26 [3] local
##   grid                   4.4.0     2023-11-26 [3] local
##   gridExtra              2.3       2017-09-09 [2] CRAN (R 4.4.0)
##   gtable                 0.3.4     2023-08-21 [2] CRAN (R 4.4.0)
##   HDF5Array              1.31.0    2023-10-24 [2] Bioconductor
##   highr                  0.10      2022-12-22 [2] CRAN (R 4.4.0)
##   htmltools              0.5.7     2023-11-03 [2] CRAN (R 4.4.0)
##   htmlwidgets            1.6.4     2023-12-06 [2] CRAN (R 4.4.0)
##   httpuv                 1.6.13    2023-12-06 [2] CRAN (R 4.4.0)
##   httr                   1.4.7     2023-08-15 [2] CRAN (R 4.4.0)
##   httr2                  1.0.0     2023-11-14 [2] CRAN (R 4.4.0)
##   ini                    0.3.1     2018-05-20 [2] CRAN (R 4.4.0)
##   IRanges                2.37.0    2023-10-24 [2] Bioconductor
##   isoband                0.2.7     2022-12-20 [2] CRAN (R 4.4.0)
##   jquerylib              0.1.4     2021-04-26 [2] CRAN (R 4.4.0)
##   jsonlite               1.8.8     2023-12-04 [2] CRAN (R 4.4.0)
##   KEGGREST               1.43.0    2023-10-24 [2] Bioconductor
##   KernSmooth             2.23-22   2023-07-10 [3] CRAN (R 4.4.0)
##   knitr                  1.45      2023-10-30 [2] CRAN (R 4.4.0)
##   labeling               0.4.3     2023-08-29 [2] CRAN (R 4.4.0)
##   later                  1.3.2     2023-12-06 [2] CRAN (R 4.4.0)
##   lattice                0.22-5    2023-10-24 [3] CRAN (R 4.4.0)
##   lazyeval               0.2.2     2019-03-15 [2] CRAN (R 4.4.0)
##   leaflet                2.2.1     2023-11-13 [2] CRAN (R 4.4.0)
##   leaflet.providers      2.0.0     2023-10-17 [2] CRAN (R 4.4.0)
##   lifecycle              1.0.4     2023-11-07 [2] CRAN (R 4.4.0)
##   littler                0.3.18    2023-03-26 [2] CRAN (R 4.4.0)
##   magrittr               2.0.3     2022-03-30 [2] CRAN (R 4.4.0)
##   MASS                   7.3-60.1  2023-11-26 [3] local
##   Matrix                 1.6-4     2023-11-30 [3] CRAN (R 4.4.0)
##   MatrixGenerics         1.15.0    2023-10-24 [2] Bioconductor
##   matrixStats            1.2.0     2023-12-11 [2] CRAN (R 4.4.0)
##   memoise                2.0.1     2021-11-26 [2] CRAN (R 4.4.0)
##   methods              * 4.4.0     2023-11-26 [3] local
##   mgcv                   1.9-0     2023-07-11 [3] CRAN (R 4.4.0)
##   mime                   0.12      2021-09-28 [2] CRAN (R 4.4.0)
##   miniUI                 0.1.1.1   2018-05-18 [2] CRAN (R 4.4.0)
##   MultiAssayExperiment   1.29.0    2023-10-24 [2] Bioconductor
##   munsell                0.5.0     2018-06-12 [2] CRAN (R 4.4.0)
##   nlme                   3.1-164   2023-11-27 [3] CRAN (R 4.4.0)
##   nnet                   7.3-19    2023-05-03 [3] CRAN (R 4.4.0)
##   openssl                2.1.1     2023-09-25 [2] CRAN (R 4.4.0)
##   parallel               4.4.0     2023-11-26 [3] local
##   pillar                 1.9.0     2023-03-22 [2] CRAN (R 4.4.0)
##   pkgbuild               1.4.2     2023-06-26 [2] CRAN (R 4.4.0)
##   pkgconfig              2.0.3     2019-09-22 [2] CRAN (R 4.4.0)
##   pkgdown                2.0.7     2022-12-14 [2] CRAN (R 4.4.0)
##   pkgload                1.3.3     2023-09-22 [2] CRAN (R 4.4.0)
##   plogr                  0.2.0     2018-03-25 [2] CRAN (R 4.4.0)
##   plotly                 4.10.3    2023-10-21 [2] CRAN (R 4.4.0)
##   png                    0.1-8     2022-11-29 [2] CRAN (R 4.4.0)
##   praise                 1.0.0     2015-08-11 [2] CRAN (R 4.4.0)
##   preprocessCore         1.65.0    2023-10-24 [2] Bioconductor
##   prettyunits            1.2.0     2023-09-24 [2] CRAN (R 4.4.0)
##   processx               3.8.2     2023-06-30 [2] CRAN (R 4.4.0)
##   profvis                0.3.8     2023-05-02 [2] CRAN (R 4.4.0)
##   promises               1.2.1     2023-08-10 [2] CRAN (R 4.4.0)
##   proxy                  0.4-27    2022-06-09 [2] CRAN (R 4.4.0)
##   ps                     1.7.5     2023-04-18 [2] CRAN (R 4.4.0)
##   purrr                  1.0.2     2023-08-10 [2] CRAN (R 4.4.0)
##   R6                     2.5.1     2021-08-19 [2] CRAN (R 4.4.0)
##   ragg                   1.2.6     2023-10-10 [2] CRAN (R 4.4.0)
##   RaggedExperiment       1.27.0    2023-10-24 [2] Bioconductor
##   rappdirs               0.3.3     2021-01-31 [2] CRAN (R 4.4.0)
##   raster                 3.6-26    2023-10-14 [2] CRAN (R 4.4.0)
##   rcmdcheck              1.4.0     2021-09-27 [2] CRAN (R 4.4.0)
##   RColorBrewer           1.1-3     2022-04-03 [2] CRAN (R 4.4.0)
##   Rcpp                   1.0.11    2023-07-06 [2] CRAN (R 4.4.0)
##   RCurl                  1.98-1.13 2023-11-02 [2] CRAN (R 4.4.0)
##   rematch2               2.1.2     2020-05-01 [2] CRAN (R 4.4.0)
##   remotes                2.4.2.1   2023-07-18 [2] CRAN (R 4.4.0)
##   rhdf5                  2.47.1    2023-11-29 [2] Bioconductor 3.19 (R 4.4.0)
##   rhdf5filters           1.15.1    2023-11-06 [2] Bioconductor
##   Rhdf5lib               1.25.1    2023-12-11 [2] Bioconductor 3.19 (R 4.4.0)
##   rlang                  1.1.2     2023-11-04 [2] CRAN (R 4.4.0)
##   rmarkdown              2.25      2023-09-18 [2] CRAN (R 4.4.0)
##   roxygen2               7.2.3     2022-12-08 [2] CRAN (R 4.4.0)
##   rpart                  4.1.23    2023-12-05 [3] CRAN (R 4.4.0)
##   rprojroot              2.0.4     2023-11-05 [2] CRAN (R 4.4.0)
##   RSQLite                2.3.4     2023-12-08 [2] CRAN (R 4.4.0)
##   rstudioapi             0.15.0    2023-07-07 [2] CRAN (R 4.4.0)
##   rversions              2.1.2     2022-08-31 [2] CRAN (R 4.4.0)
##   s2                     1.1.5     2023-12-10 [2] CRAN (R 4.4.0)
##   S4Arrays               1.3.1     2023-11-27 [2] Bioconductor 3.19 (R 4.4.0)
##   S4Vectors              0.41.2    2023-11-23 [2] Bioconductor 3.19 (R 4.4.0)
##   sass                   0.4.8     2023-12-06 [2] CRAN (R 4.4.0)
##   scales                 1.3.0     2023-11-28 [2] CRAN (R 4.4.0)
##   sessioninfo            1.2.2     2021-12-06 [2] CRAN (R 4.4.0)
##   sf                     1.0-14    2023-07-11 [2] CRAN (R 4.4.0)
##   shiny                  1.8.0     2023-11-17 [2] CRAN (R 4.4.0)
##   sourcetools            0.1.7-1   2023-02-01 [2] CRAN (R 4.4.0)
##   sp                     2.1-2     2023-11-26 [2] CRAN (R 4.4.0)
##   SparseArray            1.3.1     2023-11-07 [2] Bioconductor
##   spatial                7.3-17    2023-07-20 [3] CRAN (R 4.4.0)
##   splines                4.4.0     2023-11-26 [3] local
##   stats                * 4.4.0     2023-11-26 [3] local
##   stats4                 4.4.0     2023-11-26 [3] local
##   stringi                1.8.3     2023-12-11 [2] CRAN (R 4.4.0)
##   stringr                1.5.1     2023-11-14 [2] CRAN (R 4.4.0)
##   SummarizedExperiment   1.33.1    2023-11-28 [2] Bioconductor 3.19 (R 4.4.0)
##   survival               3.5-7     2023-08-14 [3] CRAN (R 4.4.0)
##   sys                    3.4.2     2023-05-23 [2] CRAN (R 4.4.0)
##   systemfonts            1.0.5     2023-10-09 [2] CRAN (R 4.4.0)
##   tcltk                  4.4.0     2023-11-26 [3] local
##   terra                  1.7-55    2023-10-13 [2] CRAN (R 4.4.0)
##   testthat               3.2.1     2023-12-02 [2] CRAN (R 4.4.0)
##   textshaping            0.3.7     2023-10-09 [2] CRAN (R 4.4.0)
##   tibble                 3.2.1     2023-03-20 [2] CRAN (R 4.4.0)
##   tidyr                  1.3.0     2023-01-24 [2] CRAN (R 4.4.0)
##   tidyselect             1.2.0     2022-10-10 [2] CRAN (R 4.4.0)
##   tinytex                0.49      2023-11-22 [2] CRAN (R 4.4.0)
##   tools                  4.4.0     2023-11-26 [3] local
##   units                  0.8-5     2023-11-28 [2] CRAN (R 4.4.0)
##   urlchecker             1.0.1     2021-11-30 [2] CRAN (R 4.4.0)
##   usethis                2.2.2     2023-07-06 [2] CRAN (R 4.4.0)
##   utf8                   1.2.4     2023-10-22 [2] CRAN (R 4.4.0)
##   utils                * 4.4.0     2023-11-26 [3] local
##   vctrs                  0.6.5     2023-12-01 [2] CRAN (R 4.4.0)
##   vipor                  0.4.5     2017-03-22 [2] CRAN (R 4.4.0)
##   viridis                0.6.4     2023-07-22 [2] CRAN (R 4.4.0)
##   viridisLite            0.4.2     2023-05-02 [2] CRAN (R 4.4.0)
##   waldo                  0.5.2     2023-11-02 [2] CRAN (R 4.4.0)
##   whisker                0.4.1     2022-12-05 [2] CRAN (R 4.4.0)
##   withr                  2.5.2     2023-10-30 [2] CRAN (R 4.4.0)
##   wk                     0.9.1     2023-11-29 [2] CRAN (R 4.4.0)
##   xfun                   0.41      2023-11-01 [2] CRAN (R 4.4.0)
##   xml2                   1.3.6     2023-12-04 [2] CRAN (R 4.4.0)
##   xopen                  1.0.0     2018-09-17 [2] CRAN (R 4.4.0)
##   xtable                 1.8-4     2019-04-21 [2] CRAN (R 4.4.0)
##   XVector                0.43.0    2023-10-24 [2] Bioconductor
##   yaml                   2.3.8     2023-12-11 [2] CRAN (R 4.4.0)
##   YESCDS                 0.99.3    2023-12-13 [2] Github (vjcitn/YESCDS@26ad809)
##   YESCDSbook             0.98.4    2023-12-13 [1] local
##   zip                    2.3.0     2023-04-17 [2] CRAN (R 4.4.0)
##   zlibbioc               1.49.0    2023-10-24 [2] Bioconductor
##  
##   [1] /tmp/Rtmpt8bwcZ/Rinstb4a46155c
##   [2] /usr/local/lib/R/site-library
##   [3] /usr/local/lib/R/library
##  
##  ───────────────────────────────────────────────────────────────────────────
Back to top